A Brief Description of MTP Kit (Mifepristone and Misoprostol Pills)
MTP Kit is one of the safe and cost-effective medications that is used for finishing pregnancy in women that have been pregnant for 63 days or less. MTP possesses two active drug moieties known as Mifepristone and Misoprostol that are the safest and effective drugs for the therapeutic execution of pregnancy.
Mechanism of Action of MTP Kit (Mifepristone and Misoprostol Pills)
Mifepristone is a synthetic steroid with having anti-progestational activity. It has the ability to get bind to the progesterone receptor competitively and averts the endometrial and myometrial effects of progesterone. During pregnancy, Mifepristone helps in the contraction of myometrium that is the inducing action of prostaglandin. It further causes cervix dilation and softening, the release of endogenous prostaglandins and trophoblast detachment. Therefore, results in the termination of pregnancy. Misoprostol is an analog of prostaglandin. Misoprostol causes the softening of the cervix, contraction of myometrium and cervix softening. Therefore, results in the expulsion of the uterine contents.
The Dosage Regimen of MTP Kit (Mifepristone and Misoprostol Pills)
On the first day, a woman has to administer one tablet of Mifepristone 200 mg orally with plenty of water. On the third day, the woman has to take four tablets of Misoprostol 200 mcg (800 mcg) either via oral route or via vaginal route. Approximately 14 days after the administration of Mifepristone, the woman has to prefer a follow-up visit to the hospital for confirming the complete termination of the pregnancy.
Contraindications of MTP Kit
If a woman is allergic or hypersensitive to Mifepristone, Misoprostol or any other ingredient present in MTP Kit, then the woman should not take this medication.
Precautions while taking MTP Kit (Mifepristone and Misoprostol Pills)
- If you already have IUCD, then it should be removed before taking the MTP Kit. MTP Kit should not be used.
- If the pregnancy of a woman is outside the uterus also known as ectopic pregnancy.
- MTP Kit should be used with extreme caution in elderly patients. In case you have an ongoing pregnancy and if you are a lactating mother, then you should not take this medication.
- If you are suffering from kidney, liver, lungs or cardiovascular diseases, stroke, diabetes, high blood pressure, anemia, then you should avoid taking this medication.
Side Effects of MTP Kit (Mifepristone and Misoprostol Pills)
Some common side effects of MTP Kit include abdominal pain, diarrhea, back pain, nausea, vomiting, headache, dizziness, sweating, and vaginal bleeding.